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Evaluating the safety and effectiveness of huo xue hua yu therapy for non-alcoholic fatty liver disease


In this study, researchers at Jinan University and Guangzhou Medical University evaluated the effectiveness and safety of huo xue hua yu (HXHY) therapy for non-alcoholic fatty liver disease (NAFLD). They reported their findings in an article published in the journal BMC Complementary and Alternative Medicine.

  • For their systematic review and meta-analysis, the researchers conducted comprehensive searches in various databases, such as Embase, Pubmed, Cochrane Library, CNKI, VIP and Wanfang, for randomized clinical trials (RCTs) until June 2017.
  • They pooled studies that used HXHY as NAFLD treatment and compared the herbal medicine with conventional treatment.
  • Their meta-analysis included 13 studies involving 1,429 patients.
  • Of these, 775 belonged to the HXHY group while 654 patients belonged to the conventional treatment group.
  • The researchers found that HXHY can significantly improve the results of B ultrasound for NAFLD patients compared with conventional treatment.
  • HXHY was also much better at reducing total cholesterol and triglycerides than conventional treatment.
  • In addition, HXHY exerted a greater effect on liver function by reducing alanine transaminase and aspartate transaminase levels.
  • HXHY was found to be significantly more effective than conventional treatment without causing adverse reactions.

Based on these findings, the researchers concluded that HXHY is an effective and safe natural medicine for NAFLD.

Read the full study at this link.

Journal Reference:

Cai Y, Liang Q, Chen W, Chen M, Chen R, Zhang Y, Xiao Y, Chen L. EVALUATION OF HUOXUEHUAYU THERAPY FOR NONALCOHOLIC FATTY LIVER DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIAL. BMC Complementary and Alternative Medicine. 19 July 2019;19(1). DOI: 10.1186/s12906-019-2596-3

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